Description
“Cartimov™ capsules is indicated for Treatment of symptoms in patients with osteoarthritis of the hip or knee, with delayed effect”
“Diacerein 50 mg.
Diacerein’s active metabolite rhein reduces cartilage destruction by decreasing expression of matrix metalloproteinase (MMP)-1 and -3 as well as up regulating tissue inhibitor of matrix metalloproteinases which
serve to reduce the activity of several (MMPs).
The anti-inflammatory action of rhein reduces the level of interleukin-1beta activity which plays a large role in reduction of extracellular matrix production, (MMP) activity, and continued inflammation.
Rhein reduces abnormal osteoblast synthetic activity through an unknown mechanism.”
Category: Pain & Inflammation
“Cartimov™ capsules is indicated for Treatment of symptoms in patients with osteoarthritis of the hip or knee, with delayed effect”